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The Research Seminar is a weekly space that focuses on various areas of applied mathematics, with special emphasis on Mathematical Optimization and Modeling. The main objective is to share the research results of the Modemat and put the researchers of the Center in contact with academics from all over the world, in person or through virtual platforms. Organizer of the seminar: Sergio González Andrade. To subscribe to the Seminar mailing list or propose a talk in it, please write to: sergio.gonzalez@epn.edu.ec

Physics-informed neural networks for cardiac activation mapping

Physics-informed neural networks for cardiac activation mapping

By Dr. Francisco Sahli. Universidad de Chile

Seminar Date: 2021-12-02

Electroanatomical maps are a key tool in the diagnosis and treatment of atrial fibrillation. Current approaches focus on the activation times recorded. However, more information can be extracted from the available data. The fibers in cardiac tissue conduct the electrical wave faster, and their direction could be inferred from activation times. In this work, we employ physics informed neural networks, to learn the fiber orientations from electroanatomical maps, taking into account the physics of the electrical wave propagation. In particular, we train the neural network to weakly satisfy the anisotropic eikonal equation and to predict the measured activation times. We use a local basis for the anisotropic conductivity tensor, which encodes the fiber orientation. The methodology is tested both in a synthetic example and for patient data. Our approach shows good agreement in both cases, with an RMSE of 2.2ms on the in-silico data and outperforming a state of the art method on the patient data. The results show a first step towards learning the fiber orientations from electroanatomical maps with physics-informed neural networks.

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